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Sept. 25, 2025, 8:50 AM EDT / Updated Sept. 25, 2025, 9:04 AM EDTBy Andrea Mitchell, Abigail Williams and Chantal Da SilvaPresident Donald Trump has assured Arab leaders that he will not allow Israel to annex the already occupied West Bank, sources told NBC News, amid fears of retaliation from the U.S. ally after a host of countries moved to recognize Palestinian statehood.Trump made the comments Tuesday, according to two sources who were in the room, as he presented his 21-point plan for peace in the Middle East to Arab leaders gathered in New York for the United Nations General Assembly. The comments were first reported by Politico.Trump’s special envoy Steve Witkoff said the meeting with leaders from countries including Qatar, the United Arab Emirates, Jordan, Egypt and Turkey was “productive.” He said a breakthrough could be imminent in efforts to bring an end to the war in the Gaza Strip, where Israel has continued a deadly military campaign to take over Gaza City.Trump calls the recognition of a Palestinian state ‘a reward’ for Hamas02:23“We presented what we call the Trump 21-point plan for peace in the Mideast, in Gaza,” Witkoff said at the Concordia Annual Summit, a conference on the sidelines of the General Assembly. “I think it addresses Israeli concerns, as well as the concerns of all the neighbors in the region. And we’re hopeful, and I might say even confident, that in the coming days, we’ll be able to announce some sort of breakthrough,” he added.Israel has intensified its attacks as troops pushed deeper into Gaza City in recent days.Moiz Salhi / Anadolu via Getty ImagesIt was not immediately clear what advances might have been made, with past promises of progress in talks failing to yield a deal to end Israel’s assault on Gaza and see hostages still held in the enclave released. The spiraling conflict in the Middle East has been a focal point of the General Assembly this week, with Palestinian President Mahmoud Abbas expected to address the gathering Thursday, albeit by video after the U.S. last month revoked his visa, along with those of other Palestinian Authority officials. Speaking with Gulf foreign ministers Wednesday during the assembly, Secretary of State Marco Rubio said: “We understand very clearly that the situation in Gaza, the situation with Israel and Gaza, is a key concern for everyone in this room here today.”“We want this conflict to end,” he said. “We want it to end immediately.”Rubio added that “some very important work is ongoing, even as we speak, and hoping to achieve this as soon as possible.”Funeral services for people killed in an Israeli military strike, outside Al-Aqsa Hospital in Deir al-Balah on Wednesday.Abdel Kareem Hana / APTrump’s assurances to Arab leaders that he would not let Israel annex the West Bank came after right-wing members of Israeli Prime Minister Benjamin Netanyahu’s fragile government coalition called for the move as a string of countries, including France, the United Kingdom, Canada, Australia and Portugal formally recognized Palestine as a state. Palestinians envision the West Bank as a core territory for an internationally recognized Palestinian state, alongside Gaza and east Jerusalem. Annexation of the territory, which has been occupied by Israel since 1967, would further imperil that cause. The bodies of people killed by an Israeli army attack on the Firas Market in Gaza City, on Wednesday.Hamza Z. H. Qraiqea / Anadolu via Getty ImagesNetanyahu, who was traveling to New York on Thursday before addressing the General Assembly on Friday and meeting Trump next week, has declared that there will never be a Palestinian state under his watch.Trump told the U.N. this week that the recognition moves risked rewarding Hamas.Israel has already pushed ahead with a widely condemned settlement plan that would effectively split the West Bank in two, further fracturing what Palestinians envision as their future state.Deadly settler violence and Israeli military operations have also increased in the Palestinian territory.UAE leaders have said annexation of the West Bank would be a red line for the influential Gulf state, blocking any future recognition of Israel and preventing the completion of Trump’s landmark Abraham Accords that sought to establish diplomatic normalization between Israel and several Arab states.Andrea MitchellAndrea Mitchell is chief Washington correspondent and chief foreign affairs correspondent for NBC News.Abigail WilliamsAbigail Williams is a producer and reporter for NBC News covering the State Department.Chantal Da SilvaChantal Da Silva reports on world news for NBC News Digital and is based in London.

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Oct. 20, 2025, 12:33 PM EDTBy Rebecca CohenThe news is out and the internet is thrilled: Colman Domingo will voice the Cowardly Lion in “Wicked: For Good.” “Wicked” director Jon M. Chu teased the news in a Thursday interview with Deadline, saying that it will be “wild” when the actor who is voicing the part — a major Hollywood star, per Chu — steps on the red carpet. But the news was instead revealed Monday, when the “Wicked” movie Instagram account posted a video of Domingo playing with and surrounded by a number of stuffed toy lions. “See you in Oz,” Domingo says in the video with a wink. Users on social media spent the weekend speculating who might be playing the part, with rumors centering on former late-night host and musical theater actor James Corden. When the news was announced Monday, those same users celebrated the casting — and the fact that the role didn’t go to Corden. “James Corden isn’t the lion in wicked! We won,” one X user posted. In order to book Domingo in the part originally made famous by Bert Lahr in the 1939 film adaptation of “The Wizard of Oz,” Chu told Deadline he sent the “Sing Sing” actor a direct message on Instagram. “I was like, ‘It’s not a ton of lines, but maybe you have a little time. I know you’re busy. I’ll come to you,'” Chu recalled saying in the message, according to Deadline. Chu said Domingo responded “‘Why the f— not, let’s go!’ And then we went ahead and recorded the lines.”Domingo joins an already star-studded cast, including Ariana Grande as Glinda, Cynthia Erivo as Elphaba and Jonathan Bailey as Fiyero. “Wicked: For Good,” the second in a two-part series, releases in theaters on Nov. 21. It will continue the story told in last year’s “Wicked.” The film is produced and will be distributed by Universal Pictures, which is owned by NBCUniversal, the parent company of NBC News.Rebecca CohenRebecca Cohen is a breaking news reporter for NBC News Digital.

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Savewith a NBCUniversal ProfileCreate your free profile or log in to save this articleOct. 1, 2025, 11:00 AM EDTBy Liz SzaboPeople who learn they have autism after age 6 — the current median age at diagnosis — are often described as having a “milder” form of autism than people diagnosed as toddlers.A new study challenges that assumption.A genetic analysis finds that people with autism spectrum disorder diagnosed in late childhood or adolescence actually have “a different form of autism,” not a less severe one, said Varun Warrier, senior author of a study published Wednesday in Nature.The “genetic profile” of people with late-diagnosis autism actually looks more like depression, attention-deficit/hyperactivity disorder and post-traumatic stress disorder than early childhood autism, said Warrier, an autism researcher at the University of Cambridge. The study illustrates that autism is not a single condition with one root cause, but rather an umbrella term for a cluster of conditions with similar — although not identical — features, said Geraldine Dawson, founding director of the Duke Center for Autism and Brain Development, who wasn’t involved in the new report. Alycia Halladay, chief science officer at the Autism Science Foundation, who wasn’t involved in the study, said: “This paper reinforces yet again how complex autism is and how much genetics plays a role not just in a diagnosis but in the features of that diagnosis. There is no one cause of autism, despite claims against Tylenol.”Authors of the new study analyzed long-term social, emotional and behavioral information about children in the United Kingdom and Australia, as well as genetic data about more than 45,000 autistic people in Europe and the United States.Different genetic profilesResearchers didn’t focus on a single gene or even a few genes. Instead, they looked at sets of thousands of genetic variants that together influence particular traits. While one genetic profile may lead to difficulties with social interactions during the toddler or preschool years, another set of genes may cause an increase in such problems during late childhood and beyond, Warrier said.The new study suggests that some autistic children “develop differently and may not receive a diagnosis earlier on because their features may not yet have clearly emerged,” Warrier said. “It is important to understand what these features are and ensure that we are assessing autistic people across the lifespan.”Most autism diagnoses are made before age 18, with 22% of diagnoses occurring by age 4, 20% from 5 to 8, 15% from 9 to 12 and 16% from 13 to 17.Adult diagnoses are more common in women. Twenty-five percent of women with autism were diagnosed at age 19 or older last year, compared with 12% of men, according to Epic Research.In the study, adolescents diagnosed with autism had more difficulties managing emotional issues and relationships with peers than other kids. That was the struggle for Adeline Lacroix of Toronto. Lacroix, now 42, who was raised in France, had trouble making friends as a child. She “wondered why in school we learned things that were to me quite easy, such as mathematics, but we didn’t learn how to make friends, which for me was much more difficult,” she said.Lacroix often didn’t understand when other people were being ironic or making a joke. Although she got good grades, “I felt I was very dumb because I didn’t understand a lot of things.”Adeline Lacroix’s life changed when she was diagnosed with autism at age 30.Courtesy Adeline LacroixHer frustration led to depression and thoughts of death. “I didn’t really want to die, but at the same time I was so tired,” she said.Her life changed when she was diagnosed with autism at age 30. Suddenly, she realized why understanding conversations was so hard. She changed careers, abandoning her old job as a schoolteacher to pursue a doctorate in psychology and neuroscience. Lacroix now has a supportive partner and a job she loves at the Center for Addiction and Mental Health in Toronto, where she researches women and girls with autism. “I’m very happy with my life,” she said.Although many young people with autism are still diagnosed relatively late in childhood because of a lack of screening and resources in their communities, increased awareness and wider access to testing have helped lower the age at which children are diagnosed with autism, allowing them to get critical early support. Increased acceptance of neurodiversity is also motivating a growing number of teens and adults to seek out testing for autism, which can involve difficulties in communication and social interactions, as well as restricted or repetitive behaviors or interests. From 2011 to 2022, autism diagnoses among adults 26 to 34 grew by 450%, the largest relative increase among any age group.In the Nature study, the first to link a genetic profile to the timing of autism diagnosis, newly diagnosed adolescents had an increased risk of depression.The increase in depression could stem from both a genetic predisposition and a lack of support faced by young people whose unique learning needs and social challenges go unaddressed for years, Warrier said.“Children who have undiagnosed autism may not receive the support they need,” he said. “They may be bullied, excluded and may be vulnerable socially. It is only when they are struggling that caregivers seek out professional help and they receive an autism diagnosis.”In future research, he said, Warrier hopes to study how a person’s social environment — whether supportive or hostile — affects the risk of depression in later-diagnosed people. Although school and community services often focus on youngsters, Warrier said it’s important to support people with autism of all ages.The emotional toll of trying to blend inSam Brandsen, who grew up in a small town in Iowa where few people were familiar with autism, didn’t get that critical support. In the sixth grade, he was bullied for being different. Kids made fun of him for rocking back and forth, a behavior that he found soothing. Boys shoved him into lockers and tied his shoelaces to his desk to make him fall.By force of will, he managed to sit still at his desk. But the mental and emotional effort he expended took a heavy toll, Brandsen said, causing him to suffer panic attacks between classes.“You know that you’re different, but you don’t really have a framework for understanding what that difference is,” said Sam Brandsen who was diagnosed with autism at 27.Sam BrandsonBrandsen, now 31, said he wasn’t diagnosed with autism until four years ago, after his 18-month-old son was diagnosed with it. Like Lacroix, Brandsen said he felt relieved to better understand himself. Instead of wasting energy to act like everyone else, he said, “I’d rather use that energy to just be a kinder person.”Brandsen said he can understand why people with autism who are diagnosed later in life may have a greater risk of mental distress.“You know that you’re different, but you don’t really have a framework for understanding what that difference is,” said Brandsen, a part-time postdoctoral researcher at the University of Alberta in Canada and a member of the Autism Society’s Council of Autistic Advisors. “You’re trying to make sense of rules that seem to make sense to everyone else, and you don’t know why it’s not clicking for you.”Although Brandsen said he understands why scientists want to study the causes of autism, he said he hopes they will spend more time researching ways to help people with autism lead full, independent lives. His son has a number of disabilities, Brandsen said, but the boy also experiences tremendous joy.“There’s so many ways that he’s changed my life profoundly for the better, even if it’s been kind of a harder path at times,” Brandsen said. “But then he can also take so much joy from just watching a train.”If you or someone you know is in crisis, call or text 988, or go to 988lifeline.org, to reach the Suicide & Crisis Lifeline. You can also call the network, previously known as the National Suicide Prevention Lifeline, at 800-273-8255, or visit SpeakingOfSuicide.com/resources.Liz SzaboLiz Szabo is an independent health and science journalist. Her work has won multiple national awards. One of her investigations led to a new state law in Virginia.

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