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September 24, 2025

Sept. 23, 2025, 7:55 PM EDTBy Liz Szabo and Lauren DunnDr. Heidi Leftwich, a maternal-fetal medicine specialist at UMass Memorial Health, said she has gotten many more questions about acetaminophen from some of her pregnant patients in recent weeks.The safety of the fever and pain reliever “comes up periodically,” especially when there’s a news story about it, said Dr. Allison Bryant, a maternal-fetal medicine specialist at Mass General Brigham.Rather than scare them or dictate what they should do, Bryant said, she favors “shared decision-making” with her patients, with them “at the center” of her guidance.At a news briefing Monday, President Donald Trump promoted unproven claims that taking acetaminophen during pregnancy was linked to a risk of autism in children. The Food and Drug Administration has sent a letter telling doctors to “consider minimizing the use of acetaminophen,” the active ingredient in Tylenol and a wide range of other over-the-counter medications, for routine low-grade fevers in pregnant women.Trump’s announcement came after several weeks of reports about the warning. Pregnant women experiencing pain or fever should “tough it out,” Trump said.Dr. Laura Riley, chief of obstetrics and gynecology at Weill Cornell Medicine in New York, said patients have come in since Trump’s briefing anxious and unsure what to do. “There was a lot of head-shaking,” Riley said. Are doctors changing their guidance about acetaminophen? More than half of women worldwide use acetaminophen during pregnancy. It is used in hundreds of products, including cough and cold treatments. Doctors said in interview that their advice hasn’t changed, in spite of the Trump administration’s concerns.“We normally advise women with pain or fever to take acetaminophen, unless there is some other reason why we think it might be unsafe,” such as when women have allergies or pre-existing liver disease, Bryant said. Riley said the most common reasons pregnant women take acetaminophen are fever, headache and low back pain. “I’m telling women not to do anything differently than what we started with, which was Tylenol is one of the best pain relievers that we have in pregnancy,” she said.Untreated fever, especially in the first three months of pregnancy, increases the risk of miscarriage, birth defects and premature birth, according to the Society for Maternal-Fetal Medicine. Fever in the second and third trimesters can trigger contractions and may be associated with early labor, Riley said, so “it’s important to treat.”Emily Heumann, 31, was 10 or 12 weeks pregnant when she spiked a fever of 104 degrees because of a viral infection. She’d developed hand, foot and mouth disease — a highly contagious virus that typically spreads among children — after she was infected by her 4-year-old son. The infection causes sores in the mouth and a rash on the hands and feet.Heumann said that although her son experienced only minor symptoms that went away quickly, she experienced severe pain for 10 days, especially because of sores in her throat and inside her ears.Her doctor told her that it was important to bring her temperature down and suggested she take acetaminophen, often sold under the brand name Tylenol.“If the Tylenol didn’t work, they said to go to the emergency room,” said Heumann, who is now 36 weeks pregnant.Bryant suggests that women with questions about any medication during pregnancy talk to doctors they trust and who know them well.Both the American College of Obstetrics and Gynecology and the Society of Maternal Fetal Medicine continue to recommend acetaminophen as safe for pregnant women and say the bulk of medical evidence doesn’t show a link to autism. Bryant noted that the groups base their advice on the total body of evidence about acetaminophen and neurodevelopment disorders, not just one study.“That guidance is not likely to change anytime soon,” Bryant said.Leftwich said she feels comfortable talking with her patients about the treatment of fever and pain with acetaminophen during pregnancy. “This is a very important conversation to have with a trusted physician.”Untreated pain in pregnancy can be risky, tooRiley said that after Trump warned about acetaminophen use during pregnancy, she’s had patients asking, “‘the next time I get a headache, what should I do?’” Her response: “Take Tylenol.” “There’s no reason for you to tough it out,” Riley said. “That’s not an appropriate way of managing pain.” If women ask Bryant about research suggesting a link between acetaminophen and autism, she tells them that the strongest, most rigorous study to examine the question found no association between acetaminophen use during pregnancy and autism, attention-deficit/hyperactivity disorder or intellectual disability.An important feature of that study of more than 2.4 million children, published last year in JAMA, is that it included siblings of children with autism as a control group. Autism tends to run in families, with twins or siblings of people with autism having a higher risk.Leftwich said Heumann’s doctor did right by putting the patient first and keeping her needs in mind.“Instilling undue fear in pregnant individuals could lead to inadequate management of fever and pain,” Leftwich said, adding that untreated pain is associated with depression, anxiety and high blood pressure, which can increase the risk of preterm births.Heumann said she is grateful that her doctor suggested acetaminophen for her fever, which began to fall within an hour of her taking the medication. Acetaminophen also helped relieve the intense pain from the infection.“It was one of the worst things I’ve ever experienced,” said Heumann, 31, who lives in central Florida. When she tried to sleep at night, “laying on the sores was especially painful. The throat pain was the worst.”Lowest dose for the shortest amount of timeLeftwich said she advises pregnant women to be cautious when they use any medication. “It’s really important to talk about the judicious use of any medication,” she said. “You should use the lowest dose possible to get the treatment that you need, for instance, for fever reduction or pain control. I would say the same about Tylenol as I would for any other medication.”Heumann said pregnant women have enough to worry about without adding unproven risks.“Every mom I know feels guilt regularly,” she said. “We want what’s best for our kids so badly, and no matter what we do, most of us worry … if what we’ve done is the right thing. This just adds one more thing for moms to worry about. And it’s based in misinformation, which is so dangerous.”Kati Woock, who developed frequent migraines during her pregnancy five years ago, said her doctor reassured her that taking acetaminophen — one of the ingredients in her usual migraine treatment — was safe.“Sometimes with a migraine, I can’t even be vertical,” said Woock, 36, who lives in Illinois.Woock said she was with family members when she developed the first migraine of her pregnancy, which occurred mainly during the first three to four months. Her family told her, “You shouldn’t take anything when you’re pregnant because you’re going to hurt the baby,” Woock recalled. “I was kind of nervous about it, but I decided that my doctor probably knew what she was talking about.”Liz SzaboLiz Szabo is an independent health and science journalist. Her work has won multiple national awards. One of her investigations led to a new state law in Virginia.Lauren DunnLauren Dunn is the executive editor of the NBC News Medical Unit.

October 8, 2025

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October 6, 2025

Oct. 6, 2025, 5:35 AM EDTBy Mithil Aggarwal and Larissa GaoChinese rescuers were on Monday rushing to evacuate hundreds of hikers stranded on the eastern slope of the world’s highest mountain, Mount Everest, after heavy snowfall blanketed campsites over the weekend.Nearly 350 hikers have already traveled to safety at a rendezvous point in the small township of Qudang, according to state broadcaster CCTV, with rescuers also in contact with the remaining over 200 hikers who “will gradually arrive at the rendezvous point.”Local news outlets had initially reported that nearly 1,000 people had been affected by the blizzard. Local rescue officials were not immediately available for comment on the discrepancy in numbers.No casualties were reported, according to local media. Trekkers leaving their campsite as unusually heavy snow and rainfall pummeled the Himalayas on Sunday.Geshuang Chen / via Reuters“About one-third into the trek, it began to rain and the rain kept getting heavier,” Chen Geshuang, a 28-year-old astrophotographer who began climbing Saturday afternoon but decided to retreat Sunday, told NBC News in an online video interview. “Later, it turned into sleet, and eventually a full-on blizzard.”Some hikers shoveled snow out of their tents amid the blizzard, while others waded in a line through the snowstorm in poor visibility, social media videos verified by NBC News showed.The hikers had been trapped at nearly 16,000 feet, according to a report in Jimu News, which added that local villagers and rescue teams had been deployed to clear the roads blocked by snow. Everest Base Camp.Yulia Y / Getty ImagesAt 29,000 feet, Mount Everest is considered the world’s tallest mountain when measured from sea level.The unusually intense snowfall began Friday night and continued through Saturday in the Gama Valley of Tingri County in the autonomous region of Tibet, “disrupting the itineraries of some tourists hiking in the area,” CCTV said.Within hours, some of Chen’s team were exhibiting signs of mild hypothermia and cold stress, she said. By Saturday night, the storm intensified with lightning almost every minute. “It was a nerve-wracking night,” she said. “When we woke up this morning, the snow was extremely deep— about one meter, reaching up to our thighs.”The group decided to retreat, arriving at the foot of the mountain Sunday evening. Neighboring Nepal was also hit with heavy rainfall, where at least 44 people were killed from landslides and floods. The severe weather event occurred as more than 299 million people were expected to travel regionally on Sunday due to a weeklong national holiday that included China’s National Day last week and the Mid-Autumn Festival on Monday, CCTV said in a separate report.Ticket sales and entry to the Everest Scenic Area was suspended late Saturday, according to notices on the official WeChat accounts of the local Tingri County Tourism Company.Mount Everest is called Mount Qomolangma in Chinese, and it stretches along the border of Tibet and Nepal, and climbers from both countries attempt to scale the peak along different slopes.While the Nepalese side has seen a boom in Everest-related tourism and significant investment, the Tibetan side is especially remote. Mithil AggarwalMithil Aggarwal is a Hong Kong-based reporter/producer for NBC News.Larissa GaoLarissa Gao is an associate social newsgathering reporter based in London.Reuters and Peter Guo contributed.

September 26, 2025

Sept. 26, 2025, 11:24 AM EDTBy Rob Wile and Steve KopackAnalysts are already warning that U.S. consumers could see higher prices due to new tariffs President Donald Trump plans to impose on drug product imports as soon as next week.But a series of exemptions may blunt the ultimate impact. In a Truth Social post late Thursday, Trump said that any branded or patented pharmaceutical products brought into the U.S. would face a 100% tariff starting Oct. 1.U.S. imports of pharmaceuticals totaled about $213 billion in 2024, a threefold increase from a decade earlier, according to data from the United Nations Comtrade Database.With Asia alone accounting for just over 20% of those imports by value, U.S. consumers could see a “meaningful commercial hit,” Louise Loo, head of Asia economics at Oxford Economics research group, said in a note to clients. Previous studies have shown that U.S. annual spending per capita on prescription drugs is about double the rest of the developed world. In July, Trump announced a plan to “get Americans the best prices in the world for prescription drugs” that involved asking major drugmakers to match low prices they offer elsewhere in the world. However, it is not clear what actions the pharma firms have taken to begin addressing that demand. The pharmaceutical industry is already warning that the new tariffs could derail further drug development while also raising prices. “Every dollar spent on tariffs is a dollar that cannot be invested in American manufacturing or the development of future treatments and cures,” Alex Schriver, senior vice president for PhRMA, the drug industry’s primary lobbying group, said in a statement. “Medicines have historically been exempt from tariffs because they raise costs and could lead to shortages.”Despite those warnings, a significant share of drug products could wind up being exempted from the new import duties. The tariffs do not appear to apply to so-called generic drugs, which account for 9 out of 10 prescriptions filled in the U.S., according to the Food and Drug Administration. The White House did not immediately respond to a request to confirm the exemption for generics, but assuming they will remain tariff-free, the impact to consumers could be more limited than feared. Trump also specified that any drug companies that currently have, or have committed to building, U.S.-based drug-making facilities would be exempted from tariffs. That’s a category that includes numerous major drugmakers. “Many pharmaceutical companies have facilities in the U.S., so it may be relatively easy to superficially expand those facilities to avoid tariffs being applied,” Paul Donovan, chief global economist at UBS Global Wealth Management, wrote in a note to clients. Analysts at JPMorgan agreed: “While there remains very limited details, we note that this will likely lead to a majority of pharma products being excluded from any tariffs” because most major companies have recently increased or have started to increase their U.S. manufacturing facilities.On the White House website, the administration maintains a “running list of new U.S. investment” from private companies. At least 15 pharmaceutical or drug makers are listed with investments ranging from new manufacturing facilities, tens of billions in expanded U.S. production and increased R&D spending. Many of those announcements would appear to meet the requirements laid out by Trump to avoid the new tariff.Two major European drugmakers, Roche and Novartis, said in statements that they expected little to no impact from the newly announced duties. “We are working to ensure that all major Novartis medicines for U.S. patients are manufactured in the U.S.,” Novartis said in a statement. “The announced 100% tariff should not have an impact.” Roche pointed to ongoing factory construction in the U.S., with multiple sites being expanded and upgraded in Kentucky, Indiana, New Jersey and California.Trump has signaled since at least April that drug imports would face tariffs. In anticipation, major drugmakers have indicated they have been stockpiling supplies, analysts said. As a result, consumers are unlikely to feel immediate effects even though the tariffs are set to kick in next week. “We think there may have been significant inventory accumulation this year,” Neil Shearing, group chief economist with Capital Economics, said in a note. This summer, Trump placed a maximum 15% tariff on most pharmaceuticals coming in from the European Union, which accounts for 60% of drugs imported by the U.S. E.U. officials believe that this agreement will shield it from the 100% duties, though they said they could not be certain. “This clear all-inclusive 15% tariff ceiling for E.U. exports represents an insurance policy that no higher tariffs will emerge for European economic operators,” a European Commission spokesperson told NBC News on Friday.Ireland’s deputy prime minister, Simon Harris, who also acts as trade minister, said his country is “studying the impact of this announcement” but added that he believed the 15% cap on pharma tariffs remained in place. Ireland alone accounts for 24% of pharma imports to the U.S.Rob WileRob Wile is a Pulitzer Prize-winning journalist covering breaking business stories for NBCNews.com.Steve KopackSteve Kopack is a senior reporter at NBC News covering business and the economy.

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