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Trump receives Covid vaccine during physical

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Trump receives Covid vaccine during physical

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Oct. 11, 2025, 12:30 PM EDT / Updated Oct. 11, 2025, 3:57 PM EDTBy Mirna AlsharifNo one is believed to have survived a powerful explosion at an explosives plant in Tennessee, officials said Saturday, as crews continue to recover remains from the blast site.“I can tell you that more than 300 people have been through almost every square inch of this facility, and at this time we’ve recovered no survivors,” Humphreys County Sheriff Chris Davis said at a news briefing.Davis would not share how many people were killed in the Friday-morning blast, saying, “We’re in the process of the identification of the remains.”“We can probably make the assumption, and I’m not even going to use the word assumption — I think that we can utilize, well, I have to use that word, forgive me — we can assume that they are deceased at this point.”Davis said that the cause of the blast at Accurate Energetic Systems near McEwen is still under investigation, and that he cannot rule out foul play.“That might be days or weeks or months before we can do that,” he said.The blast happened at around 7:45 a.m. Friday morning and “encompassed one whole building,” according to Davis.Officials on Friday said at least 18 people who were at the plant were unaccounted for. On Saturday, they did not provide an update on those individuals, reporting only that no survivors had been recovered.Search operations at the site of the explosion continued overnight as officials notified families waiting on word about their loved ones.Satellite image show the explosives plant in Humphreys County, Tenn., before and after the explosion on Friday.Satellite image 2025 VantorSatellite images from the scene of the blast show nothing remaining of the facility other than scattered debris.“As we get into this, we find it even more devastating than what we thought initially,” Davis said.Special Agent Guy McCormick with the Bureau of Alcohol, Tobacco, Firearms and Explosives said there are certified explosives specialists and bomb technicians on the scene to help make the area safe.“In a situation like this, what we find is that when these explosives are subject to the event that took place — which is heat, the explosion being thrown, pressure — they can change, and they can become different than how we know them to act,” McCormick said on Saturday.On Friday evening, a group of people gathered nearby in Centerville to hold a vigil after hearing about the blast. Attendees held candles and prayed. Felicity Howell, a nurse at Hickman County Middle School, was in her kitchen on Friday morning when she heard the explosion.”There was a huge boom and my house shook very, like, hard,” she said. “It honestly felt like a vehicle drove through our house. That’s what I thought whenever it happened. But then we found out it was the explosion that was about 10 miles down the road.” Accurate Energetic Systems on Friday extended thoughts and prayers in a statement to affected families, employees and community members. The privately owned facility, which processes ammunition and explosives, did not share any additional details on the explosion.The facility established a family assistance center to provide support for those affected by the incident, according to the Tennessee Emergency Management Agency (TEMA).There is no known threat to the public as a result of the blast, TEMA said. The agency is asking the public to avoid the area so emergency personnel can do their work “safely and efficiently.”“Residents who locate debris that may have originated from the explosion are asked to contact their local sheriff’s office,” TEMA said. “Trained personnel will respond to ensure the safe handling and collection of any debris.”The investigation into the incident is ongoing, officials said.The FBI is also assisting with the investigation.Mirna AlsharifMirna Alsharif is a breaking news reporter for NBC News.

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By Berkeley Lovelace Jr.President Donald Trump will announce Tuesday that his administration has reached an agreement with Pfizer to voluntarily sell its drugs at lower prices, according to a White House official. The official, however, did not specify which drugs would be affected or by how much. Nor was it clear whether the lower prices would be available only for people on government insurance such as Medicaid or those with private insurance.Pfizer, among the largest drugmakers in the U.S., makes a range of drugs, including the blood thinner Eliquis, the cancer drug Ibrance, and the Covid vaccine. The deal is part of Trump’s broader effort to implement a “most favored nation” pricing model for prescription drugs, meaning that the U.S. pays no more than the lowest prices charged in other wealthy countries.In May, Trump signed an executive order outlining the initiative, which directed federal officials to pursue a plan that would tie the amount the government pays for certain drugs to the prices paid overseas. Pfizer — the first drugmaker to announce a deal under the plan — will “reduce prices across the board,” a White House official said. The company will also sell its drugs on a “direct to consumer” website called “TrumpRx,” the official said. The company will also announce a $70 billion investment in research and development and domestic manufacturing, the official said.Pfizer did not immediately respond to a request for comment. Prescription drugs prices are notoriously higher in the U.S. than in other wealthy countries.A 2022 survey by KFF, a nonpartisan health policy research group, found 3 in 4 U.S. adults say the cost of medications is unaffordable. This is a developing story. Please check back for updates.Berkeley Lovelace Jr.Berkeley Lovelace Jr. is a health and medical reporter for NBC News. He covers the Food and Drug Administration, with a special focus on Covid vaccines, prescription drug pricing and health care. He previously covered the biotech and pharmaceutical industry with CNBC.

November 8, 2025

Savewith a NBCUniversal ProfileCreate your free profile or log in to save this articleNov. 8, 2025, 5:00 AM ESTBy Mithil AggarwalNEW DELHI — When the weight loss drug Mounjaro came on the market in India earlier this year, Shyamanthak Kiran was one of the first patients to try it.Kiran, a 27-year-old financial trader who has struggled with hypothyroidism, said he “did not have a lot of expectations” when it came to losing weight. But “luck turned out in my favor,” he said, and in six months he lost all of the 60-plus pounds he had gained a few years earlier.“It was a two-year struggle that came to an end, and I couldn’t be happier,” he told NBC News.Indians trying to lose weight are embracing drugs such as Mounjaro, which is also used to treat diabetes in a country that has been called the world’s diabetes capital. The injectable medication from American pharmaceutical company Eli Lilly has become India’s most popular drug by value since being approved in March, with over $11 million in sales in October, pharmaceutical market research firm Pharmarack said Friday.Mounjaro is an injectable medication used to treat diabetes. Saumya Khandelwal for NBC NewsEven before India’s more recent approval of Ozempic, another drug that is widely used for weight loss in the United States and other countries, there was already surging demand in the country for semaglutide, its active ingredient.Ozempic’s Danish drugmaker, Novo Nordisk, says it is “actively working” to widen the availability of the drug, which Indian regulators have approved for diabetes but not obesity. The company also makes other semaglutide drugs that are already used for weight loss in India, including Wegovy, an injectable, and Rybelsus, which is taken orally.Demand could grow even further when the patent for Ozempic’s active ingredient, semaglutide, expires next March in India, a pharmaceutical manufacturing giant where companies are eager to produce cheaper generic versions of the lucrative weight-loss drugs.The exploding popularity of the drugs has taken aback some doctors and officials, with Jitendra Singh, a government minister and physician, warning in August against the “unchecked spread of disinformation” through “fad regimens” and emphasizing the importance of lifestyle interventions such as regular yoga practice.Semaglutide and tirzepatide, the active ingredient in Mounjaro, are GLP-1 agonists that were first developed to treat diabetes and have also been approved in many countries for the treatment of obesity. They regulate blood sugar and help slow how quickly food passes through the stomach, curbing hunger as a result.India, the world’s most populous country, has over 100 million people with diabetes, or nearly 10% of its adult population, according to a 2023 study by the Indian Council of Medical Research. An additional 135 million people are prediabetic, the study found.Diabetes information displayed on the walls of a clinic in New Delhi last month.Saumya Khandelwal for NBC NewsDoctors say the situation is worsening as India’s burgeoning middle class adopts a more Western lifestyle, eating more high-fat, high-sugar foods and exercising less.“Compared to, say, a decade ago, there are more people now in their late 20s and early 30s who are being diagnosed with diabetes, as compared to the elderly population,” said Dr. Saurav Shishir Agrawal, an endocrinologist in Noida, which is part of Delhi’s capital region.“They ask us to just give them pills,” Agrawal said, “but these medicines work better only when you are clubbing them with lifestyle changes.”Agrawal practices at the newly built Medanta Hospital, where staff greet patients with a gentle “Namaste.” It is an example of the growing number of modern and high-end hospitals popping up around increasingly dense megacities such as Delhi, home to 33 million people, where diabetes has a greater hold.Saurav Agrawal, an endocrinologist at Medanta Hospital in Noida, India.Saumya Khandelwal for NBC NewsA monthly course of Mounjaro can cost as much as $250, the average monthly salary in many parts of India. But for more affluent Indians, a bigger deterrent is the idea of injecting themselves, said Dr. Tribhuvan Gulati, an endocrinologist.“People get scared whenever you tell them that they’re going to be on an injectable,” said Gulati, who has a clinic in central Delhi.Gulati keeps a demo pen of Mounjaro in a drawer to show how easy it is to use the medicine, which just needs to be refrigerated before use.But the ease of use is also what worries Gulati and other doctors, who say many patients fail to overhaul the lifestyle and dietary habits causing or contributing to their health issues in the first place.“If you look at the causes of obesity in India, it is 90% lifestyle and 10% anything else,” said Dr. Anoop Misra, chairman of the Fortis Centre for Diabetes, Obesity and Cholesterol and head of India’s National Diabetes Obesity and Cholesterol Foundation.“The diet now is totally imbalanced because of free availability of food everywhere,” he said.The potential gastrointestinal and other side effects from the weight-loss drugs, which in the U.S. have prompted multiple lawsuits against GLP-1 makers, give some patients pause, Gulati said. But others “are OK with continuing it throughout their life because they know that they won’t be able to control themselves.”A handbook about managing diabetes at a clinic in New Delhi.Saumya Khandelwal for NBC NewsDiabetic patients such as Moinak Pal, who has high insulin resistance, say that GLP-1 drugs have been the easiest way to lose weight.“I have been fat-shamed since I was a child,” said Pal, 34, a Noida-based journalist. He said he has been losing about 3 pounds a week since he started taking Mounjaro.It was “extremely difficult for me to lose weight by conventional means,” he said.Part of the problem, Misra said, is the lifestyle in India’s sprawling and congested urban areas, where commutes can last as long as four hours round-trip. When workers get home, apps can deliver everything from food to clothes to their doorsteps in minutes.“They want quick fixes that don’t involve going on a restrictive diet or daily exercise of an hour and so on,” he said of some of his patients. “As a result, diabetes is everywhere. Every day I see patients who are young, who have uncontrolled Type 2 diabetes.”Rajendra Nath Dixit blames nobody but himself for his health problems. The retired banker had heart bypass surgery earlier this year, and before that had been spending almost 8,000 rupees ($90) a month just on his insulin.“I was fond of taking the typical Indian oily foods, samosas, chole bhature, and in the evening I would take five or six rotis,” said Dixit, 66. “Every bad habit was there.”In the five months since his surgery, Dixit has switched over completely to the oral semaglutide Rybelsus, is exercising more and is consuming less fat and sugar. He is spending 11,000 rupees ($125) a month on Rybelsus, but has been able to stop using insulin.“I’m feeling very good, very light,” he said. “My confidence has gone up, and my life has totally changed.”Mithil AggarwalMithil Aggarwal is a Hong Kong-based reporter/producer for NBC News.

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