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US and Ukrainian Officials Meet to Broker an End to Russia's War

admin - Latest News - December 1, 2025
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After a high-stakes meeting in Florida between U.S. and Ukrainian officials, the White House is now sending its special envoy to Moscow for face-to-face talks with Vladimir Putin and voicing optimism. It comes as Russia targeted Ukrainian troops and civilians in Kyiv over the weekend, killing one person and wounding others, including children, according to local officials. NBC’s Richard Engel reports for TODAY.



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September 24, 2025
Savewith a NBCUniversal ProfileCreate your free profile or log in to save this articleSept. 24, 2025, 5:49 PM EDT / Updated Sept. 24, 2025, 6:03 PM EDTBy Babak DehghanpishehIranian President Masoud Pezeshkian lashed out at the U.S and Israel for their attacks in June during a speech at the United Nations on Wednesday, one day after Supreme Leader Ayatollah Ali Khamenei, the highest authority in the country, ruled out talks with President Donald Trump about Iran’s nuclear program.“The aerial assaults of [Israel] and the United States of America against Iran’s cities, homes and infrastructure, precisely at a time when we were treading the path of diplomatic negotiations, constituted a grave betrayal of diplomacy and a subversion of efforts towards the establishment of stability and peace,” he said. At the podium, Pezeshkian held up a book with the words “Killed By Israel” printed on the front and leafed through pages with pictures of families and children. There have been calls among moderates in Iran for direct talks with Trump, but on Tuesday Khamenei rejected negotiations with the U.S. about the country’s nuclear program and in many ways set the parameters of what Pezeshkian could discuss in New York.Trump: Iran ‘can never be allowed to possess the most dangerous weapon’01:56“In my view, negotiating with America about the nuclear issue and maybe other issues is an absolute dead end,” Khamenei said in an address, adding that Iran would not stop uranium enrichment because it would not be acceptable to the people of the country, according to his official website. He added, “This negotiation will be beneficial for the current American president. He will hold his head high, say I threatened Iran and I brought them to the negotiating table. He will be proud of this in the world. But for us it’s an absolute loss and has no benefit.”Khamenei also said on Tuesday that Iran does not intend to build a nuclear weapon, a point that Pezeshkian highlighted in his speech Wednesday, and that it will not negotiate on its ballistic missile program.NBC News has reached out to the White House for comment.Khamenei’s remarks came as the Trump administration appeared to be showing a willingness to hold talks. Trump’s Middle East envoy, Steve Witkoff, said Wednesday that Iran is in a tough position and that the administration wants to negotiate with it, according to Reuters.”We’re talking to them,” Witkoff said when asked if there is a diplomatic path forward with Iran.But the hard line drawn by Khamenei against talks with Trump about the nuclear issue could significantly ramp up tensions with the U.S. and Israel.The value of the Iranian rial against the U.S. dollar hit a record low Wednesday after Khamenei’s remarks.Moderate voices in Iran pushing for direct talks with the U.S. were hoping to stave off more devastating attacks on the country by either the Israeli or U.S. military, which pummeled the Fordo, Natanz and Isfahan nuclear sites in late June with airstrikes, including the first combat use of massive “bunker buster” bombs. Trump, addressing the United Nations on Tuesday, said the attacks had targeted “Iran’s key nuclear facility, totally obliterating everything.” But analysts have raised questions about the extent of the damage caused by the attacks and the whereabouts of the approximately 880 pounds of enriched uranium that Iran is thought to have produced.The Israeli attacks, which Israeli officials said were intended to stop the Islamic Republic from obtaining a nuclear weapon, also hammered nuclear targets but expanded to include energy infrastructure and even the country’s notorious Evin prison, and killed more than 1,000 people, according to state media.Even if Iran does not talk to the U.S. directly, Pezeshkian and his foreign minister, Abbas Araghchi, only have until Sep. 27 to negotiate a diplomatic solution with Britain, France and Germany before they face a “snapback” of sanctions. Negotiated under the 2015 nuclear deal, the snapback would lead to an arms embargo, freezing of assets outside the country and restrictions on enriching uranium, among other penalties.The sanctions could hit at a time when the country is reeling from an economic crisis, which critics blame on current sanctions as well as corruption and mismanagement. French President Emmanuel Macron met with Pezeshkian on the sidelines of the U.N. meeting in New York on Wednesday and posted on X that a diplomatic solution to avoid snapback could still be reached if Iran allows full access to inspectors from the International Atomic Energy Agency, is transparent about its stockpile of enriched materials and resumes negotiations. “An agreement remains possible. Only a few hours are left,” Macron wrote. “It is up to Iran to respond to the legitimate conditions we have set.”In recent months, Pezeshkian has been fighting for his political, and actual, life. He narrowly escaped an Israeli attack on a meeting of top officials in June, and his conservative critics have pressed him hard on the economy as well as restrictions on social freedoms. Security forces kicked off a massive crackdown during and after the war. The crackdown was ostensibly to ferret out spies, but in many cases the security forces used the war as a pretext to detain ethnic and religious minorities as well as Afghan migrants, according to Amnesty International. A police spokesman said in mid-August that 21,000 people had been arrested in the 12-day period of the war and observers say that more arrests have subsequently taken place and pending executions have been expedited. “They’re targeting already marginalized groups even further, and that’s one way for them to exert and show the control that they have and try to retain their power while also instilling fear in the population,” said Nassim Papayianni, an Iran campaigner at Amnesty International. “You’re talking about scapegoating. So essentially they are trying to use the conflict as a way to ramp up the crackdown and the arrests.”With Pezeshkian’s hands tied on the international stage by the supreme leader and his hard-line opponents pressing a crackdown on real and perceived enemies at home, the Iranian president appears more isolated than at any point since assuming his position last year. Babak DehghanpishehBabak Dehghanpisheh is an NBC News Digital international editor based in New York.
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Savewith a NBCUniversal ProfileCreate your free profile or log in to save this articleNov. 8, 2025, 5:00 AM ESTBy Mithil AggarwalNEW DELHI — When the weight loss drug Mounjaro came on the market in India earlier this year, Shyamanthak Kiran was one of the first patients to try it.Kiran, a 27-year-old financial trader who has struggled with hypothyroidism, said he “did not have a lot of expectations” when it came to losing weight. But “luck turned out in my favor,” he said, and in six months he lost all of the 60-plus pounds he had gained a few years earlier.“It was a two-year struggle that came to an end, and I couldn’t be happier,” he told NBC News.Indians trying to lose weight are embracing drugs such as Mounjaro, which is also used to treat diabetes in a country that has been called the world’s diabetes capital. The injectable medication from American pharmaceutical company Eli Lilly has become India’s most popular drug by value since being approved in March, with over $11 million in sales in October, pharmaceutical market research firm Pharmarack said Friday.Mounjaro is an injectable medication used to treat diabetes. Saumya Khandelwal for NBC NewsEven before India’s more recent approval of Ozempic, another drug that is widely used for weight loss in the United States and other countries, there was already surging demand in the country for semaglutide, its active ingredient.Ozempic’s Danish drugmaker, Novo Nordisk, says it is “actively working” to widen the availability of the drug, which Indian regulators have approved for diabetes but not obesity. The company also makes other semaglutide drugs that are already used for weight loss in India, including Wegovy, an injectable, and Rybelsus, which is taken orally.Demand could grow even further when the patent for Ozempic’s active ingredient, semaglutide, expires next March in India, a pharmaceutical manufacturing giant where companies are eager to produce cheaper generic versions of the lucrative weight-loss drugs.The exploding popularity of the drugs has taken aback some doctors and officials, with Jitendra Singh, a government minister and physician, warning in August against the “unchecked spread of disinformation” through “fad regimens” and emphasizing the importance of lifestyle interventions such as regular yoga practice.Semaglutide and tirzepatide, the active ingredient in Mounjaro, are GLP-1 agonists that were first developed to treat diabetes and have also been approved in many countries for the treatment of obesity. They regulate blood sugar and help slow how quickly food passes through the stomach, curbing hunger as a result.India, the world’s most populous country, has over 100 million people with diabetes, or nearly 10% of its adult population, according to a 2023 study by the Indian Council of Medical Research. An additional 135 million people are prediabetic, the study found.Diabetes information displayed on the walls of a clinic in New Delhi last month.Saumya Khandelwal for NBC NewsDoctors say the situation is worsening as India’s burgeoning middle class adopts a more Western lifestyle, eating more high-fat, high-sugar foods and exercising less.“Compared to, say, a decade ago, there are more people now in their late 20s and early 30s who are being diagnosed with diabetes, as compared to the elderly population,” said Dr. Saurav Shishir Agrawal, an endocrinologist in Noida, which is part of Delhi’s capital region.“They ask us to just give them pills,” Agrawal said, “but these medicines work better only when you are clubbing them with lifestyle changes.”Agrawal practices at the newly built Medanta Hospital, where staff greet patients with a gentle “Namaste.” It is an example of the growing number of modern and high-end hospitals popping up around increasingly dense megacities such as Delhi, home to 33 million people, where diabetes has a greater hold.Saurav Agrawal, an endocrinologist at Medanta Hospital in Noida, India.Saumya Khandelwal for NBC NewsA monthly course of Mounjaro can cost as much as $250, the average monthly salary in many parts of India. But for more affluent Indians, a bigger deterrent is the idea of injecting themselves, said Dr. Tribhuvan Gulati, an endocrinologist.“People get scared whenever you tell them that they’re going to be on an injectable,” said Gulati, who has a clinic in central Delhi.Gulati keeps a demo pen of Mounjaro in a drawer to show how easy it is to use the medicine, which just needs to be refrigerated before use.But the ease of use is also what worries Gulati and other doctors, who say many patients fail to overhaul the lifestyle and dietary habits causing or contributing to their health issues in the first place.“If you look at the causes of obesity in India, it is 90% lifestyle and 10% anything else,” said Dr. Anoop Misra, chairman of the Fortis Centre for Diabetes, Obesity and Cholesterol and head of India’s National Diabetes Obesity and Cholesterol Foundation.“The diet now is totally imbalanced because of free availability of food everywhere,” he said.The potential gastrointestinal and other side effects from the weight-loss drugs, which in the U.S. have prompted multiple lawsuits against GLP-1 makers, give some patients pause, Gulati said. But others “are OK with continuing it throughout their life because they know that they won’t be able to control themselves.”A handbook about managing diabetes at a clinic in New Delhi.Saumya Khandelwal for NBC NewsDiabetic patients such as Moinak Pal, who has high insulin resistance, say that GLP-1 drugs have been the easiest way to lose weight.“I have been fat-shamed since I was a child,” said Pal, 34, a Noida-based journalist. He said he has been losing about 3 pounds a week since he started taking Mounjaro.It was “extremely difficult for me to lose weight by conventional means,” he said.Part of the problem, Misra said, is the lifestyle in India’s sprawling and congested urban areas, where commutes can last as long as four hours round-trip. When workers get home, apps can deliver everything from food to clothes to their doorsteps in minutes.“They want quick fixes that don’t involve going on a restrictive diet or daily exercise of an hour and so on,” he said of some of his patients. “As a result, diabetes is everywhere. Every day I see patients who are young, who have uncontrolled Type 2 diabetes.”Rajendra Nath Dixit blames nobody but himself for his health problems. The retired banker had heart bypass surgery earlier this year, and before that had been spending almost 8,000 rupees ($90) a month just on his insulin.“I was fond of taking the typical Indian oily foods, samosas, chole bhature, and in the evening I would take five or six rotis,” said Dixit, 66. “Every bad habit was there.”In the five months since his surgery, Dixit has switched over completely to the oral semaglutide Rybelsus, is exercising more and is consuming less fat and sugar. He is spending 11,000 rupees ($125) a month on Rybelsus, but has been able to stop using insulin.“I’m feeling very good, very light,” he said. “My confidence has gone up, and my life has totally changed.”Mithil AggarwalMithil Aggarwal is a Hong Kong-based reporter/producer for NBC News.
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